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Family-Based Association Studies for Next-Generation Sequencing

An individual's disease risk is determined by the compounded action of both common variants, inherited from remote ancestors, that segregated within the population and rare variants, inherited from recent ancestors, that segregated mainly within pedigrees. Next-generation sequencing (NGS) techn...

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Detalhes bibliográficos
Main Authors: Zhu, Yun, Xiong, Momiao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370281/
https://ncbi.nlm.nih.gov/pubmed/22682329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.04.022
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