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p27(kip1) Protein Levels Reflect a Nexus of Oncogenic Signaling during Cell Transformation

SV40 small t-antigen (ST) collaborates with SV40 large T-antigen (LT) and activated rasv12 to promote transformation in a variety of immortalized human cells. A number of oncogenes or the disruption of the general serine-threonine phosphatase protein phosphatase 2A (PP2A) can replace ST in this para...

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Autors principals: Miller, Jeffrey P., Yeh, Nancy, Hofstetter, Christoph P., Keskin, Doruk, Goldstein, Andrew S., Koff, Andrew
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370163/
https://ncbi.nlm.nih.gov/pubmed/22511779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.361972
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