Human CCR4(+)CCR6(+)Th17 cells suppress autologous CD8(+) T cell responses

The role of Th17 cells in cancer patients remains unclear and controversial. In this study, we have analyzed the phenotype of in vitro primed Th17 cells and further characterized their function on the basis of CCR4 and CCR6 expression. We show a novel function for a subset of IL-17 secreting CD4(+)...

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Détails bibliographiques
Auteurs principaux: Zhao, Fei, Hoechst, Bastian, Gamrekelashvili, Jaba, Ormandy, Lars A., Voigtländer, Torsten, Wedemeyer, Heiner, Ylaya, Kris, Wang, Xin Wei, Hewitt, Stephen M., Manns, Michael P., Korangy, Firouzeh, Greten, Tim F.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370143/
https://ncbi.nlm.nih.gov/pubmed/22615204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102918
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