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Primary sterile necrotic cells fail to cross-prime CD8(+) T cells

Necrotic cells are known to activate the innate immune system and trigger inflammation by releasing damage associated molecular patterns (DAMPs). However, how necrotic cells influence the induction of antigen-specific CD8(+) T cell-mediated adaptive immune responses under sterile conditions, in the...

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Detalhes bibliográficos
Main Authors: Gamrekelashvili, Jaba, Ormandy, Lars A., Heimesaat, Markus M., Kirschning, Carsten J., Manns, Michael P., Korangy, Firouzeh, Greten, Tim F.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494616/
https://ncbi.nlm.nih.gov/pubmed/23170250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21098
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