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Human Th17 cells in patients with cancer: Friends or foe?

The role of interleukin-17 (IL-17)-secreting CD4(+) T (Th17) cells in cancer is under intense investigation. We have demonstrated that CCR4(+)CCR6(+) Th17 cells not only are increased in the peripheral blood of patients affected by hepatocellular carcinoma, but also suppress CD8(+) T-cell functions...

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Hlavní autoři: Greten, Tim F., Zhao, Fei, Gamrekelashvili, Jaba, Korangy, Firouzeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518530/
https://ncbi.nlm.nih.gov/pubmed/23243621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21245
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