Human CCR4(+)CCR6(+)Th17 cells suppress autologous CD8(+) T cell responses

The role of Th17 cells in cancer patients remains unclear and controversial. In this study, we have analyzed the phenotype of in vitro primed Th17 cells and further characterized their function on the basis of CCR4 and CCR6 expression. We show a novel function for a subset of IL-17 secreting CD4(+)...

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Detalhes bibliográficos
Main Authors: Zhao, Fei, Hoechst, Bastian, Gamrekelashvili, Jaba, Ormandy, Lars A., Voigtländer, Torsten, Wedemeyer, Heiner, Ylaya, Kris, Wang, Xin Wei, Hewitt, Stephen M., Manns, Michael P., Korangy, Firouzeh, Greten, Tim F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370143/
https://ncbi.nlm.nih.gov/pubmed/22615204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102918
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