Peptidases released by necrotic cells control CD8(+) T cell cross-priming

Cross-priming of CD8(+) T cells and generation of effector immune responses is pivotal for tumor immunity as well as for successful anticancer vaccination and therapy. Dead and dying cells produce signals that can influence Ag processing and presentation; however, there is conflicting evidence regar...

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Autors principals: Gamrekelashvili, Jaba, Kapanadze, Tamar, Han, Miaojun, Wissing, Josef, Ma, Chi, Jaensch, Lothar, Manns, Michael P., Armstrong, Todd, Jaffee, Elizabeth, White, Ayla O., Citrin, Deborah E., Korangy, Firouzeh, Greten, Tim F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809774/
https://ncbi.nlm.nih.gov/pubmed/24216478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65698
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