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The Cytoskeletal Adaptor Protein IQGAP1 Regulates TCR-mediated Signaling and F-actin Dynamics()

The Ras GTPase-activating-like protein IQGAP1 is a multi-modular scaffold that controls signaling and cytoskeletal regulation in fibroblasts and epithelial cells. However, the functional role of IQGAP1 in T cell development, activation and cytoskeletal regulation has not been investigated. Herein, w...

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Detalhes bibliográficos
Main Authors: Gorman, Jacquelyn A., Babich, Alexander, Dick, Christopher J., Schoon, Renee A., Koenig, Alexander, Gomez, Timothy S., Burkhardt, Janis K., Billadeau, Daniel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370139/
https://ncbi.nlm.nih.gov/pubmed/22573807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103487
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