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The WAVE2 Complex Regulates Actin Cytoskeletal Reorganization and CRAC-Mediated Calcium Entry during T Cell Activation

BACKGROUND: The engagement of the T cell receptor results in actin cytoskeletal reorganization at the immune synapse (IS) and the triggering of biochemical signaling cascades leading to gene regulation and, ultimately, cellular activation. Recent studies have identified the WAVE family of proteins a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nolz, Jeffrey C., Gomez, Timothy S., Zhu, Peimin, Li, Shuixing, Medeiros, Ricardo B., Shimizu, Yoji, Burkhardt, Janis K., Freedman, Bruce D., Billadeau, Daniel D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779663/
https://ncbi.nlm.nih.gov/pubmed/16401421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2005.11.036
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