Kv1.3 deletion biases T cells towards an immuno-regulatory phenotype and renders mice resistant to autoimmune encephalomyelitis()

Increasing evidence suggests ion channels have critical functions in the differentiation and plasticity of T cells. Kv1.3, a voltage-gated K(+) channel, is a functional marker and a pharmacological target for activated effector memory T cells. Selective Kv1.3 blockers have been shown to inhibit prol...

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Detaylı Bibliyografya
Asıl Yazarlar: Gocke, Anne R., Lebson, Lori A., Grishkan, Inna V., Hu, Lina, Nguyen, Hai M., Whartenby, Katharine A., Chandy, K. George, Calabresi, Peter A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370138/
https://ncbi.nlm.nih.gov/pubmed/22581856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103095
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