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Cutting Edge: The Transcription Factor Kruppel-Like Factor 4 Regulates the Differentiation of Th17 Cells Independently of RORγt

Th17 cells play a significant role in inflammatory and autoimmune responses. Although a number of molecular pathways that contribute to the lineage differentiation of T cells have been discovered, the mechanisms by which lineage commitment occurs are not fully understood. Transcription factors play...

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Detalhes bibliográficos
Main Authors: Lebson, Lori, Gocke, Anne, Rosenzweig, Jason, Alder, Jonathan, Civin, Curt, Calabresi, Peter A., Whartenby, Katharine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071015/
https://ncbi.nlm.nih.gov/pubmed/21076063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002750
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