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Aminopeptidase Substrate Preference Impacts HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-infected Persons
Viruses evade immune detection partly through immune-associated mutations. Analyses of HIV sequences derived from infected persons have identified numerous examples of HLA-associated mutations within or adjacent T cell epitopes, but the potential impact of most mutations on epitope production and pr...
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Main Authors: | , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370117/ https://ncbi.nlm.nih.gov/pubmed/22586036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200219 |
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