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Differential HIV epitope processing in monocytes and CD4 T cells affects cytotoxic T lymphocyte recognition

The ability of cytotoxic T lymphocytes (CTL) to clear virus-infected cells is dependent on the presentation of viral peptides processed intracellularly and displayed by MHC-I. Most CTL functional assays utilize exogenously added peptides, which does not account for kinetics and quantity of antigenic...

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Detalhes bibliográficos
Main Authors: Lazaro, Estibaliz, Godfrey, Sasha Blue, Stamegna, Pamela, Ogbechie, Tobi, Kerrigan, Christopher, Zhang, Mei, Walker, Bruce D., Le Gall, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724235/
https://ncbi.nlm.nih.gov/pubmed/19505257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/599837
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