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Characterization of a Novel Respiratory Syncytial Virus-Specific Human Cytotoxic T-Lymphocyte Epitope

Respiratory syncytial virus (RSV) infection is a major cause of morbidity in childhood worldwide. The first human RSV-specific cytotoxic T-lymphocyte epitope to be defined is described. This HLA B7-restricted epitope in nucleoprotein (NP) was detectable in four healthy, B7-positive adult subjects us...

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Detalhes bibliográficos
Main Authors: Goulder, Philip J. R., Lechner, Franziska, Klenerman, Paul, McIntosh, Kenneth, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112296/
https://ncbi.nlm.nih.gov/pubmed/10906229
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