Immunization of Macaques with Formalin-Inactivated Respiratory Syncytial Virus (RSV) Induces Interleukin-13-Associated Hypersensitivity to Subsequent RSV Infection

Respiratory syncytial virus (RSV) is a major cause of severe respiratory disease in infants and the elderly. RSV vaccine development has been hampered by results of clinical trials in the 1960s, when formalin-inactivated whole-RSV preparations adjuvated with alum (FI-RSV) were found to predispose in...

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Autori principali: de Swart, Rik L., Kuiken, Thijs, Timmerman, Helga H., Amerongen, Geert van, van den Hoogen, Bernadette G., Vos, Helma W., Neijens, Herman J., Andeweg, Arno C., Osterhaus, Albert D. M. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136757/
https://ncbi.nlm.nih.gov/pubmed/12388717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11561-11569.2002
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