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Progress toward Positive Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5 (mGlu(5))

[Image: see text] This Review describes recent trends in the development of small molecule mGlu(5) positive allosteric modulators (PAMs). A large body of pharmacological, genetic, electrophysiological, and in vivo behavioral evidence has accumulated over the past decade which continues to support th...

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Autor principal: Stauffer, Shaun R.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2011
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369763/
https://ncbi.nlm.nih.gov/pubmed/22860171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn2000519
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