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Point Mutations in Aβ Induce Polymorphic Aggregates at Liquid/Solid Interfaces
[Image: see text] A pathological hallmark of Alzheimer’s disease (AD), a late onset neurodegenerative disease, is the development of neuritic amyloid plaques, composed predominantly of aggregates of the β-amyloid (Aβ) peptide. It has been demonstrated that Aβ can aggregate into a variety of polymorp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2011
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369758/ https://ncbi.nlm.nih.gov/pubmed/22778873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200001k |
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