Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and Liver

The comprehensive characterization of recombinant adeno-associated viral (rAAV) integration frequency and persistence for assessing rAAV vector biosafety in gene therapy is severely limited due to the predominance of episomal rAAV vector genomes maintained in vivo. Introducing rAAV insertional stand...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Nowrouzi, Ali, Penaud-Budloo, Magalie, Kaeppel, Christine, Appelt, Uwe, Le Guiner, Caroline, Moullier, Philippe, Kalle, Christof von, Snyder, Richard O, Schmidt, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369298/
https://ncbi.nlm.nih.gov/pubmed/22453768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.47
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi