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Pregnane X receptor as a target for treatment of inflammatory bowel disorders
Pregnane X receptor (PXR; NR1I2), a member of the nuclear receptor superfamily, has a major role in the induction of genes involved in drug transport and metabolism. Recent studies in mice have provided insight into a novel function for PXR in inflammatory bowel disease (IBD). The mechanisms of the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368991/ https://ncbi.nlm.nih.gov/pubmed/22609277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.03.003 |
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