The ROS Scavenger, NAC, Regulates Hepatic Vα14iNKT Cells Signaling during Fas mAb-Dependent Fulminant Liver Failure

Uncontrolled systemic activation of the immune system is an early initiating event that leads to development of acute fulminant liver failure (FLF) in mice after treatment with agonistic Fas mAb. In this study, we demonstrate that treatment of mice with N-acetylcysteine (NAC), an ROS scavenger and g...

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Detalhes bibliográficos
Main Authors: Downs, Isaac, Liu, Jianfeng, Aw, Tak Yee, Adegboyega, Patrick A., Ajuebor, Maureen N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368940/
https://ncbi.nlm.nih.gov/pubmed/22701598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038051
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