The ROS Scavenger, NAC, Regulates Hepatic Vα14iNKT Cells Signaling during Fas mAb-Dependent Fulminant Liver Failure

Uncontrolled systemic activation of the immune system is an early initiating event that leads to development of acute fulminant liver failure (FLF) in mice after treatment with agonistic Fas mAb. In this study, we demonstrate that treatment of mice with N-acetylcysteine (NAC), an ROS scavenger and g...

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Detaylı Bibliyografya
Asıl Yazarlar: Downs, Isaac, Liu, Jianfeng, Aw, Tak Yee, Adegboyega, Patrick A., Ajuebor, Maureen N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368940/
https://ncbi.nlm.nih.gov/pubmed/22701598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038051
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