Diametrically opposite methylome-transcriptome relationships in high- and low-CpG promoter genes in postmitotic neural rat tissue

DNA methylation can control some CpG-poor genes but unbiased studies have not found a consistent genome-wide association with gene activity outside of CpG islands or shores possibly due to use of cell lines or limited bioinformatics analyses. We performed reduced representation bisulfite sequencing...

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Detalhes bibliográficos
Main Authors: Hartung, Theresa, Zhang, Lu, Kanwar, Rahul, Khrebtukova, Irina, Reinhardt, Matthias, Wang, Cheng, Therneau, Terry M., Banck, Michaela S., Schroth, Gary P., Beutler, Andreas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368807/
https://ncbi.nlm.nih.gov/pubmed/22415013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19565
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