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Unique DNA methylome profiles in CpG island methylator phenotype colon cancers
A subset of colorectal cancers was postulated to have the CpG island methylator phenotype (CIMP), a higher propensity for CpG island DNA methylation. The validity of CIMP, its molecular basis, and its prognostic value remain highly controversial. Using MBD-isolated genome sequencing, we mapped and c...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266035/ https://ncbi.nlm.nih.gov/pubmed/21990380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122788.111 |
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