Oral Treatment with the d-Enantiomeric Peptide D3 Improves the Pathology and Behavior of Alzheimer’s Disease Transgenic Mice

[Image: see text] Several lines of evidence suggest that the amyloid-β-peptide (Aβ) plays a central role in the pathogenesis of Alzheimer’s disease (AD). Not only Aβ fibrils but also small soluble Aβ oligomers in particular are suspected to be the major toxic species responsible for disease developm...

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Auteurs principaux: Aileen Funke, Susanne, van Groen, Thomas, Kadish, Inga, Bartnik, Dirk, Nagel-Steger, Luitgard, Brener, Oleksandr, Sehl, Torsten, Batra-Safferling, Renu, Moriscot, Christine, Schoehn, Guy, Horn, Anselm H. C., Müller-Schiffmann, Andreas, Korth, Carsten, Sticht, Heinrich, Willbold, Dieter
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2010
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368690/
https://ncbi.nlm.nih.gov/pubmed/22778851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100057j
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