Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis.
Single-stranded M13mp18 phage DNA was methylated with dimethylsulfate (DMS), and further treated with alkali to ring-open N7-methylguanine residues and yield 2-6-diamino-4-hydroxy-5N-methylformamidopyrimidine (Fapy) residues. Nucleotide incorporation during in vitro DNA synthesis on methylated templ...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1988
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3399381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.13.5879 |
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