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Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli.

Double-stranded DNA containing 7-methylguanine residues whose imidazole rings have been opened, i.e. 2,6-diamino-4-hydroxy-5-N-methylformamido-pyrimidine residues, may be prepared by treatment of DNA with dimethyl sulfate followed by prolonged incubation at pH 11.4. These substituted formamidopyrimi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chetsanga, C J, Lindahl, T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1979
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/386277/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/6.11.3673
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