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Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli.

Double-stranded DNA containing 7-methylguanine residues whose imidazole rings have been opened, i.e. 2,6-diamino-4-hydroxy-5-N-methylformamido-pyrimidine residues, may be prepared by treatment of DNA with dimethyl sulfate followed by prolonged incubation at pH 11.4. These substituted formamidopyrimi...

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Hlavní autoři: Chetsanga, C J, Lindahl, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1979
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC327965/
https://ncbi.nlm.nih.gov/pubmed/386277
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