Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis.

Single-stranded M13mp18 phage DNA was methylated with dimethylsulfate (DMS), and further treated with alkali to ring-open N7-methylguanine residues and yield 2-6-diamino-4-hydroxy-5N-methylformamidopyrimidine (Fapy) residues. Nucleotide incorporation during in vitro DNA synthesis on methylated templ...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	O'Connor, T R, Boiteux, S, Laval, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1988
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3399381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.13.5879
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