Triarylmethanes, a New Class of Cx50 Inhibitors

The paucity of specific pharmacological agents has been a major impediment for delineating the roles of gap junction (GJ) channels formed by connexin proteins in physiology and pathophysiology. Here, we used the selective optimization of side activities (SOSA) approach, which has led to the design o...

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Hlavní autoři: Bodendiek, Silke B., Rubinos, Clio, Trelles, Maria Pilar, Coleman, Nichole, Jenkins, David Paul, Wulff, Heike, Srinivas, Miduturu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2012
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368247/
https://ncbi.nlm.nih.gov/pubmed/22685432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00106
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