Triarylmethanes, a New Class of Cx50 Inhibitors

The paucity of specific pharmacological agents has been a major impediment for delineating the roles of gap junction (GJ) channels formed by connexin proteins in physiology and pathophysiology. Here, we used the selective optimization of side activities (SOSA) approach, which has led to the design o...

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Bibliografiske detaljer
Main Authors: Bodendiek, Silke B., Rubinos, Clio, Trelles, Maria Pilar, Coleman, Nichole, Jenkins, David Paul, Wulff, Heike, Srinivas, Miduturu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368247/
https://ncbi.nlm.nih.gov/pubmed/22685432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00106
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