Triarylmethanes, a New Class of Cx50 Inhibitors

The paucity of specific pharmacological agents has been a major impediment for delineating the roles of gap junction (GJ) channels formed by connexin proteins in physiology and pathophysiology. Here, we used the selective optimization of side activities (SOSA) approach, which has led to the design o...

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Detalhes bibliográficos
Main Authors: Bodendiek, Silke B., Rubinos, Clio, Trelles, Maria Pilar, Coleman, Nichole, Jenkins, David Paul, Wulff, Heike, Srinivas, Miduturu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368247/
https://ncbi.nlm.nih.gov/pubmed/22685432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00106
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