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Functional differences between kindlin-1 and kindlin-2 in keratinocytes
Integrin-β1-null keratinocytes can adhere to fibronectin through integrin αvβ6, but form large peripheral focal adhesions and exhibit defective cell spreading. Here we report that, in addition to the reduced avidity of αvβ6 integrin binding to fibronectin, the inability of integrin β6 to efficiently...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Company of Biologists
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367939/ https://ncbi.nlm.nih.gov/pubmed/22328497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.096214 |
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