von Willebrand factor (VWF) propeptide binding to VWF D′D3 domain attenuates platelet activation and adhesion

Noncovalent association between the von Willebrand factor (VWF) propeptide (VWFpp) and mature VWF aids N-terminal multimerization and protein compartmentalization in storage granules. This association is currently thought to dissipate after secretion into blood. In the present study, we examined thi...

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Bibliografski detalji
Glavni autori: Madabhushi, Sri R., Shang, Chengwei, Dayananda, Kannayakanahalli M., Rittenhouse-Olson, Kate, Murphy, Mary, Ryan, Thomas E., Montgomery, Robert R., Neelamegham, Sriram
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2012
Teme:
Platelets and Thrombopoiesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367877/
https://ncbi.nlm.nih.gov/pubmed/22452980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-387548
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