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Sensitivity of cloned muscle, heart and neuronal voltage-gated sodium channels to block by polyamines: A possible basis for modulation of excitability in vivo
Spermidine and spermine, are endogenous polyamines (PAs) that regulate cell growth and modulate the activity of numerous ion channel proteins. In particular, intracellular PAs are potent blockers of many different cation channels and are responsible for strong suppression of outward K(+) current, a...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367677/ https://ncbi.nlm.nih.gov/pubmed/22522923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.19001 |
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