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Endogenous polyamines regulate cortical neuronal excitability by blocking voltage-gated Na(+) channels

Because the excitable properties of neurons in the neocortex depend on the characteristics of voltage-gated Na(+) channels, factors which regulate those characteristics can fundamentally modify the dynamics of cortical circuits. Here, we report on a novel neuromodulatory mechanism that links the ava...

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Detalhes bibliográficos
Main Authors: Fleidervish, Ilya A., Libman, Lior, Katz, Efrat, Gutnick, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596226/
https://ncbi.nlm.nih.gov/pubmed/19020082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803464105
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