Voltage-dependent interaction of open-channel blocking molecules with gating of NMDA receptors in rat cortical neurons.

1. The mechanisms by which four adamantane derivatives (IEM-1857, -1592, -1460 and -1754) block the open NMDA-activated channel were studied at membrane voltages (Vm) from -170 to +30 mV. The rate constants of channel block (k+) and of channel unblock (k-) were measured from the fully resolvable fli...

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Detaylı Bibliyografya
Asıl Yazarlar: Antonov, S M, Johnson, J W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158928/
https://ncbi.nlm.nih.gov/pubmed/8782107
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