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Bivalent Ligand Containing Curcumin and Cholesterol as a Fluorescence Probe for Aβ Plaques in Alzheimer’s Disease

[Image: see text] A recently developed bivalent ligand BMAOI 14 (7) has been evaluated for its ability to label and detect aggregated β-amyloid (Aβ) peptide as a fluorescent probe. This probe contains curcumin as the Aβ recognition moiety and cholesterol as an anchor to the neuronal cell membrane–li...

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Bibliografiske detaljer
Main Authors: Liu, Kai, Guo, Tai L., Chojnacki, Jeremy, Lee, Hyoung-Gon, Wang, Xinglong, Siedlak, Sandra L., Rao, Wei, Zhu, Xiongwei, Zhang, Shijun
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367438/
https://ncbi.nlm.nih.gov/pubmed/22685625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200122j
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