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Protein recognition by bivalent, ‘turn-on’ fluorescent molecular probes

We show that the conversion of a known intercalating dye (i.e., thiazole orange) into a bivalent protein binder could lead to the realization of a novel class of ‘turn-on’ fluorescent molecular probes that detect proteins with high affinity, selectivity, and a high signal-to-noise (S/N) ratio. The f...

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Vydáno v:Chem Sci
Hlavní autoři: Unger-Angel, Linor, Rout, Bhimsen, Ilani, Tal, Eisenstein, Miriam, Motiei, Leila, Margulies, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502391/
https://ncbi.nlm.nih.gov/pubmed/28717444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01038a
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