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Protein recognition by bivalent, ‘turn-on’ fluorescent molecular probes
We show that the conversion of a known intercalating dye (i.e., thiazole orange) into a bivalent protein binder could lead to the realization of a novel class of ‘turn-on’ fluorescent molecular probes that detect proteins with high affinity, selectivity, and a high signal-to-noise (S/N) ratio. The f...
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| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502391/ https://ncbi.nlm.nih.gov/pubmed/28717444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01038a |
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