Heart repair by reprogramming non-myocytes with cardiac transcription factors

The adult mammalian heart possesses little regenerative potential following injury. Fibrosis due to activation of cardiac fibroblasts impedes cardiac regeneration and contributes to loss of contractile function, pathological remodeling and susceptibility to arrhythmias. Cardiac fibroblasts account f...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Song, Kunhua, Nam, Young-Jae, Luo, Xiang, Qi, Xiaoxia, Tan, Wei, Huang, Guo N., Acharya, Asha, Smith, Christopher L., Tallquist, Michelle D., Neilson, Eric G., Hill, Joseph A., Bassel-Duby, Rhonda, Olson, Eric N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367390/
https://ncbi.nlm.nih.gov/pubmed/22660318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11139
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky