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DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations

Most restriction endonucleases, including FokI, interact with two copies of their recognition sequence before cutting DNA. On DNA with two sites they act in cis looping out the intervening DNA. While many restriction enzymes operate symmetrically at palindromic sites, FokI acts asymmetrically at a n...

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Detalhes bibliográficos
Main Authors: Rusling, David A., Laurens, Niels, Pernstich, Christian, Wuite, Gijs J. L., Halford, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367207/
https://ncbi.nlm.nih.gov/pubmed/22362745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks183
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