Dissecting protein-induced DNA looping dynamics in real time

Many proteins that interact with DNA perform or enhance their specific functions by binding simultaneously to multiple target sites, thereby inducing a loop in the DNA. The dynamics and energies involved in this loop formation influence the reaction mechanism. Tethered particle motion has proven a p...

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Bibliographic Details
Main Authors: Laurens, Niels, Bellamy, Stuart R. W., Harms, August F., Kovacheva, Yana S., Halford, Stephen E., Wuite, Gijs J. L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760800/
https://ncbi.nlm.nih.gov/pubmed/19586932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp570
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