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Real-time observation of DNA looping dynamics of Type IIE restriction enzymes NaeI and NarI

Many restriction enzymes require binding of two copies of a recognition sequence for DNA cleavage, thereby introducing a loop in the DNA. We investigated looping dynamics of Type IIE restriction enzymes NaeI and NarI by tracking the Brownian motion of single tethered DNA molecules. DNA containing tw...

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Autori principali: van den Broek, Bram, Vanzi, Francesco, Normanno, Davide, Pavone, Francesco S., Wuite, Gijs J.L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326248/
https://ncbi.nlm.nih.gov/pubmed/16407332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj432
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