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Crystal structure of NaeI—an evolutionary bridge between DNA endonuclease and topoisomerase
NaeI is transformed from DNA endonuclease to DNA topoisomerase and recombinase by a single amino acid substitution. The crystal structure of NaeI was solved at 2.3 Å resolution and shows that NaeI is a dimeric molecule with two domains per monomer. Each domain contains one potential DNA recognition...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC203366/ https://ncbi.nlm.nih.gov/pubmed/10856254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.12.3110 |
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