The domain organization of NaeI endonuclease: Separation of binding and catalysis
NaeI is a remarkable type II restriction endonuclease. It must bind two recognition sequences to cleave DNA, forms a covalent protein–DNA intermediate, and is only 1 aa change away from topoisomerase and recombinase activity. The latter activities apparently derive from reactivation of a cryptic DNA...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19870/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520400/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3531 |
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