Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

Several Sox-Oct transcription factor (TF) combinations have been shown to cooperate on diverse enhancers to determine cell fates. Here, we developed a method to quantify biochemically the Sox-Oct cooperation and assessed the pairing of the high-mobility group (HMG) domains of 11 Sox TFs with Oct4 on...

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Bibliographic Details
Main Authors: Ng, Calista K. L., Li, Noel X., Chee, Sheena, Prabhakar, Shyam, Kolatkar, Prasanna R., Jauch, Ralf
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367189/
https://ncbi.nlm.nih.gov/pubmed/22344693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks153
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