Immunogenicity of Self-Associated Aggregates and Chemically Cross-Linked Conjugates of the 42 kDa Plasmodium falciparum Merozoite Surface Protein-1

Self-associated protein aggregates or cross-linked protein conjugates are, in general, more immunogenic than oligomeric or monomeric forms. In particular, the immunogenicity in mice of a recombinant malaria transmission blocking vaccine candidate, the ookinete specific Plasmodium falciparum 25 kDa p...

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Hauptverfasser: Qian, Feng, Reiter, Karine, Zhang, Yanling, Shimp, Richard L., Nguyen, Vu, Aebig, Joan A., Rausch, Kelly M., Zhu, Daming, Lambert, Lynn, Mullen, Gregory E. D., Martin, Laura B., Long, Carole A., Miller, Louis H., Narum, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366955/
https://ncbi.nlm.nih.gov/pubmed/22675476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036996
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