Evaluation of the Immunogenicity and Vaccine Potential of Recombinant Plasmodium falciparum Merozoite Surface Protein 8

The C-terminal 19-kDa domain of merozoite surface protein 1 (MSP1(19)) is the target of protective antibodies but alone is poorly immunogenic. Previously, using the Plasmodium yoelii murine model, we fused P. yoelii MSP1(19) (PyMSP1(19)) with full-length P. yoelii merozoite surface protein 8 (MSP8)....

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Autores principales: Alaro, James R., Angov, Evelina, Lopez, Ana M., Zhou, Hong, Long, Carole A., Burns, James M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416454/
https://ncbi.nlm.nih.gov/pubmed/22585960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00211-12
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