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Autoantigen Conformation Influences Both B- and T-cell Responses and Encephalitogenicity

It has become increasingly clear that only antibodies recognizing conformation-dependent epitopes of myelin oligodendrocyte glycoprotein (MOG) have a demyelinating potential in the animal model of multiple sclerosis, experimental autoimmune encephalomyelitis (EAE). Nevertheless, for the induction of...

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Autori principali: de Graaf, Katrien L., Albert, Monika, Weissert, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366859/
https://ncbi.nlm.nih.gov/pubmed/22493449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304246
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