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Pliable DNA Conformation of Response Elements Bound to Transcription Factor p63
We show that changes in the nucleotide sequence alter the DNA conformation in the crystal structures of p63 DNA-binding domain (p63DBD) bound to its response element. The conformation of a 22-bp canonical response element containing an AT spacer between the two half-sites is unaltered compared with...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293545/ https://ncbi.nlm.nih.gov/pubmed/22247550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315820 |
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