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Pliable DNA Conformation of Response Elements Bound to Transcription Factor p63

We show that changes in the nucleotide sequence alter the DNA conformation in the crystal structures of p63 DNA-binding domain (p63DBD) bound to its response element. The conformation of a 22-bp canonical response element containing an AT spacer between the two half-sites is unaltered compared with...

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Bibliografische gegevens
Hoofdauteurs: Chen, Chen, Gorlatova, Natalia, Herzberg, Osnat
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293545/
https://ncbi.nlm.nih.gov/pubmed/22247550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315820
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